Profiling of meropenem-resistant bacteria in a river receiving wastewater effluent from a pharmaceutical industrial unit

The aim of the present study was to understand seasonal occurrence and diversity species meropenem-resistant bacteria in Gumuncheon river receiving effluents from a pharmaceutical industry Seoul, Korea.Water samples were collected Kyoung-gi province during winter (January), spring (April), summer (August), fall (November) 2018. Water plated triplicate on tryptic soy agar plates containing 16 mg/L meropenem. Meropenem-resistant isolated genetically identified using 16S rRNA analysis. predominant bacterial genera Elizabethkingia, Pseudomonas, Chryseobacterium Stenotrophomonas. Among these; Pseudomonas chengduensis taiwanesis showed resistance against 15 antibiotics. To prevent spread rivers, it is necessary implement methods that can simultaneously kill multi-drug resistant remove antibioticsfrom effluent discharge. Further, stop environment, discharge water should be stringently assessed for their risk being an environmental hazard.   Key words: Carbapenem, Meropenem, Multi-drug resistant, Chryseobacterium,